Dr. Roman Simon
Post-doc
Dr. Roman Simon
Post-doc – Drug Discovery Sciences
PhD in Pharmaceutical and Medicinal Chemistry, University of Freiburg (Germany)
Project
Our work focuses on the implementation of mass spectrometry-based, physiologically relevant label-free in vitro assays in drug discovery. Mass spectrometry (MS) is an emerging technology for identifying and characterizing molecules that modulate protein function offering a label-free, direct detection method. We utilize recent advances in liquid handling technology for developing high-throughput capable MS-based readout strategies for small molecule screening and profiling campaigns.
Supervisor
Dr. Wolfgang Reindl
Laboratory Head – Drug Discovery Sciences
PhD in Biochemistry, Max Planck Institute of Biochemistry Martinsried (Germany)
Research interests:
- Assay development, high-throughput screening and compound profiling
- High-throughput MALDI-TOF MS
- Covalent inhibitors