Dr. Oana-Daniela Toader
Post-doc
Dr. Oana-Daniela Toader
Post-doc – CNS Discovery Research
PhD in Neurobiology, University of Heidelberg
Master in Neuroscience, IMPRS Neuroscience (Germany) and Italian Institute of Technology, Genova (Italy)
Project
Establishment of an in-vivo model of cognitive impairment, that will aid in identifying novel treatment options and characterizing novel cognitive enhancing drug candidates. To this aim, optogenetics will be used to inhibit specific interneurons in the prefrontal cortex of mice, which then will be analyzed by in-vivo electrophysiology and behavioral tasks to assess memory, attention and cognitive flexibility in relation to prefrontal neuronal network oscillations.
Supervisor
Dr. Holger Rosenbrock
Senior Principal Scientist, Laboratory Head CNS Discovery Research
PhD in Biochemistry & Neuroscience, University of Freiburg
Diploma in Chemistry, University of Freiburg
Research interests:
- New therapeutic concepts for treatment of cognitive dysfunction in neuropsychiatric disorders like schizophrenia and Alzheimer’s disease
- Synaptic transmission and plasticity in relation to cognitive function
- Network oscillations and EEG recordings in brain slices and rodents to investigate new therapeutic concepts for cognition